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2023 Experiential Internship - Analytical Research and Development (Illinois)

Company: AbbVie
Location: Lynchburg
Posted on: January 27, 2023

Job Description:

AbbVie's mission is to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas: immunology, oncology, neuroscience, eye care, virology, women's health, and gastroenterology, in addition to products and services across its Allergan Aesthetics portfolio.
For more information about AbbVie, please visit us at
Follow @abbvie on Twitter, Facebook, Instagram, YouTube, and LinkedIn.
Envision spending your summer working with energetic colleagues and inspirational leaders, all while gaining world-class experience in one of the most dynamic organizations in the pharmaceutical industry. This is a reality for AbbVie's Experiential Interns.
The Analytical Research & Development (Analytical R&D) organization is a world-class analytical team of more than 300 scientists that drive scientific excellence and process understanding through innovative solutions. Analytical R&D is responsible for all Chemistry, Manufacturing, and Control (CMC) analytical activities related to the development of AbbVie's products. During the internship, the intern will have the opportunity to work on key aspects of developing fundamental scientific understanding as it relates to AbbVie projects and processes.
Develop liquid chromatography-mass spectrometry (LC-MS) techniques for the in-depth characterization of therapeutic proteins
Support sample preparation for high resolution LCMS analysis

Optimize specialized protein separation techniques to enable the analysis of interested product quality attributes. Troubleshoot equipment and experimental problems

Design, develop and optimize instrumentation and separation parameters, including HPLC and high-resolution mass spectrometer, for peptide and PTM quantitation and detection
Conduct laboratory studies to investigate post-translational modifications (PTMs) occurring on therapeutic antibodies (mAbs) and antibodies drug conjugates (ADCs)
Establish an improved analytical method for PTM level analysis in our product development pipeline
Test different internal standards to improve the accuracy and reproducibility of our assays
Perform the analytical tests to characterize the structure of antibody drug conjugates (ADCs) and understand the kinetics of reactions in ADC conjugation process
Interact with cross-functional teams to establish productive collaborations
Analyze and interpret data; organize and document data in a lab notebook
Present work and results in team/group meetings
Currently enrolled in university, pursuing a Master's or PhD in Analytical Chemistry, Chemistry, Biochemistry or related field

Must be enrolled in university during the internship period

Strong written and verbal communication skills with the ability to interact effectively with interdisciplinary scientists and engineers
High attention to detail, creativity in problem solving, strong interpersonal skills and proven ability to successfully work independently and as part of teams.
Ability to work on multiple and simultaneous projects as part of a team in a global, fast-paced, setting where priorities may change quickly
Expected graduation date between December 2023 - December 2024

Previous work experience in a laboratory setting

Previous experience with operating high-resolution mass spectrometry, or protein separation techniques (ion exchange chromatography, hydrophobic interaction chromatography, capillary electrophoresis, etc.), or protein labeling and derivatization techniques required
Competitive pay

Travel, transportation and lodging support for eligible students

At AbbVie, we value bringing together individuals from diverse backgrounds to develop new and innovative solutions for patients. As an equal opportunity employer, we do not discriminate on the basis of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information gender identity or expression, sexual orientation, marital status, protected veteran status, or any other legally protected characteristic.

Keywords: AbbVie, Lynchburg , 2023 Experiential Internship - Analytical Research and Development (Illinois), Other , Lynchburg, Virginia

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